A coregulatory influence map of glioblastoma heterogeneity and plasticity - From cells in vitro to tumors and back again
Chloé Bernhard, Konstantinos Geles, Geoffrey Pawlak, Wajdi Dhifli, Aurélien Dispot, Jules Dusol, Maria Kondratova, Sophie Martin, Mélissa Messé, Damien Reita, David Tulasne, Isabelle VAN SEUNINGEN, Natacha Entz‐Werlé, Silvia Anna Ciafrè, Monique Dontenwill, Mohamed Elati
This paper introduces GBM-cRegMap, a resource that maps transcriptomic data to a coregulatory network, revealing GBM heterogeneity and identifying key regulators like NKX2.5 involved in TMZ resistance.
npj Precision Oncology · Apr 15, 2025Peer-reviewedCancer Biology