Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling
Heidrun Vethe, Thomas Aga Legøy, Shadab Abadpour, Berit Løkensgard Strand, Hanne Scholz, João A. Paulo, Helge Ræder, Luiza Ghila, Simona Chera
This study shows that encapsulating hiPSCs in alginate improves their differentiation into pancreatic islet-like cells by reshaping the proteome and activating integrin signaling pathways.
bioRxiv · Oct 4, 2019 · PreprintMolecular Biology