Discriminative feature of cells characterizes cell populations of interest by a small subset of genes
Takeru Fujii, Kazumitsu Maehara, Masatoshi Fujita, Yasuyuki Ohkawa
The paper introduces DFC, a method using adaptive LASSO logistic regression to identify a small subset of genes that distinguish cell populations, addressing issues with P-value inflation in single-cell transcriptomics.
PLoS Computational Biology · Nov 19, 2021Peer-reviewedBioinformatics