Structural studies on M. tuberculosis decaprenyl phosphoryl-β-D-ribose epimerase-2 enzyme involved in cell wall biogenesis
Shanti Pal Gangwar, Arkita Bandyopadhyay, Ajay Kumar Saxena
This paper structurally characterizes MtbDprE2, an NADH-dependent enzyme in M. tuberculosis, and elucidates its NADH binding mechanism through circular dichroism, molecular modeling, and dynamics simulations.
bioRxiv · Oct 15, 2020 · PreprintBioinformatics