Author

John Frater

John Radcliffe HospitalORCID 0000-0001-7163-7277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:Bayesian inference· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aime Bienfait IgiranezaiD· 1 shared Angela Ruth McLeaniD· 1 shared Annette OxeniusiD· 1 shared Chris WymantiD· 1 shared Christophe FraseriD· 1 shared Cloete van VuureniD· 1 shared Dominique GoedhalsiD· 1 shared Duncan S. PalmeriD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Aime Bienfait IgiranezaORCID

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2 papers

Recent·Most cited

BioinformaticsPLoS Computational BiologyPeer-reviewedNov 20, 2024

Learning patterns of HIV-1 co-resistance to broadly neutralizing antibodies with reduced subtype bias using multi-task learning

Aime Bienfait Igiraneza, Panagiota Zacharopoulou, Robert Hinch…·Christophe Fraser

This paper develops a multi-task learning model to predict HIV-1 resistance to multiple broadly neutralizing antibodies, showing it reduces subtype bias and identifies co-resistance patterns.

10 citations

humanmachine learning (classical)

𝕏 PostBluesky

GeneticsNature CommunicationsPeer-reviewedJul 9, 2019

Mapping the drivers of within-host pathogen evolution using massive data sets

Duncan S. Palmer, Isaac Turner, Sarah J. Fidler…·Gil McVean

The paper develops a Bayesian method to detect host influences on pathogen evolution using large datasets, demonstrating improved precision in identifying HLA-induced selection in HIV-1.

11 citations

humanwhole-genome sequencing

𝕏 PostBluesky