Author

Laura M.L. Hawk

Grand Valley State UniversityORCID 0000-0001-7176-3863Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Addison Chen· 1 shared Andy Kwong· 1 shared Ayan Mohamed· 1 shared Benjamin R Butler· 1 shared Carla Marie PeraltaiD· 1 shared Chloe Tannous· 1 shared Emile Tadros· 1 shared Gianmarc GrazioliiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Addison Chen

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1 paper

Recent·Most cited

BiochemistryBiochemistryPeer-reviewedJul 28, 2026

The Effects of Phosphorylation on the Structure and Function of Motif A, an Intrinsically Disordered Region within SIRT1

Sabrina M. Richter, Hoang-Long Bui, Addison Chen…·Ningkun Wang

This study investigates how phosphorylation affects the structure and function of motif A in SIRT1, showing that phosphomimetic mutation at Ser27 enhances SIRT1 activity and induces structural ordering of the disordered region.

DOI 10.1021/acs.biochem.6c00333

humanprotein structure

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