Author

Stephen Oscar Duke

Wellcome Sanger InstituteORCID 0000-0001-7210-5168Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Organism:human· 1 Approach:simulation· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Ian VermesiD· 1 shared Ludmil B. AlexandroviD· 1 shared Marcos Díaz‐GayiD· 1 shared Mark D. BarnesiD· 1 shared Michael R. StrattoniD· 1 shared Nithish Bharadhwaj Narasimman· 1 shared Paul BrennaniD· 1 shared Raviteja VangaraiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Ian VermesORCID

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1 paper

Recent·Most cited

BioinformaticsBioinformaticsPeer-reviewedDec 1, 2023

✦ In-depth digest

Assigning mutational signatures to individual samples and individual somatic mutations with SigProfilerAssignment

Marcos Díaz‐Gay, Raviteja Vangara, Mark D. Barnes…·Ludmil B. Alexandrov

SigProfilerAssignment refits known substitution, doublet, indel and copy-number mutational signatures to single samples and probabilistically to individual mutations, outperforming four refitting tools on 2,700 synthetic genomes.

194 citationstop 1%

humanwhole-genome sequencing

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