Author

Fiorella Ruggiu

insitro, inc. (United States)ORCID 0000-0001-7260-3255Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Ajamete KaykasiD· 1 shared Albert M. KimiD· 1 shared Alexis Ewer· 1 shared Bobby Leitmann· 1 shared Ci ChuiD· 1 shared Daphne KolleriD· 1 shared David Feldman· 1 shared Eilon SharoniD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Ajamete KaykasORCID

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1 paper

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedDec 16, 2025

A Pooled Cell Painting CRISPR Screening Platform Enables de novo Inference of Gene Function by Self-supervised Deep Learning

Srinivasan Sivanandan, Bobby Leitmann, Eric Lubeck…·Ci Chu

This paper introduces a pooled CRISPR screening platform combined with self-supervised deep learning to infer gene function from morphological phenotypes without target-specific biomarkers.

35 citationstop 1%

humanCRISPR screen