Distinct Motor Cortex Somatotopy in Experimental Alzheimers Disease
Sidney E Moss, Cassandra C. Wolsh, Rogers M. Brown, Andrew R. Brown, Sreeram Manchikalapudi, David Quentin Beversdorf, Lixin Ma, Jeffery A. Boychuk
This study shows that motor cortex somatotopy changes with age in 5XFAD mice, with early expansion of simple movement zones and later deterioration of both complex and simple maps.
bioRxiv · Aug 18, 2026 · PreprintNeuroscience