Duplex formation between the template and the nascent strand in the transcription-regulating sequences determines the site of template switching in SARS - CoV-2
Aaron R. D’Souza, Amanda B. Buckingham, Fanny Salasc, Carin K. Ingemarsdotter, Gennaro Iaconis, Isobel Jarvis, Harriet C. T. Groom, Julia C. Kenyon, Andrew M. L. Lever
The paper models TRS duplex stability and transcription speed to determine template switching sites in SARS-CoV-2 subgenomic RNA synthesis.
RNA Biology · Sep 20, 2021Peer-reviewedBioinformatics