Author

Adrien Nicolaı̈

Centre National de la Recherche ScientifiqueORCID 0000-0001-7779-4652Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:simulation· 1

Frequent Co-Authors

Patrice Delarue· 2 shared Patrick SenetiD· 2 shared Adrien Guzzo· 1 shared Andreina Urquiola Hernández· 1 shared Gia G. MaisuradzeiD· 1 shared Khatuna Kachlishvili· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersBiophysics

Patrice Delarue

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2 papers

Recent·Most cited

Examining the Atypical Structure Adopted by the 37-51 Segment of α-synuclein in the Early Stage of Aggregation

Adrien Guzzo, Patrice Delarue, Khatuna Kachlishvili, Adrien Nicolaı̈, Patrick Senet, Gia G. Maisuradze

This study uses molecular dynamics simulations to identify a previously unreported braid conformation in the 37-51 segment of α-synuclein that may influence aggregation.

bioRxiv · Oct 23, 2026 · PreprintBiophysics

Sequencing of α-synuclein Intrinsically Disordered Protein in MoS2 Nanopores

Adrien Nicolaı̈, Patrice Delarue, Andreina Urquiola Hernández, Patrick Senet

This paper uses molecular dynamics simulations to study α-synuclein translocation through MoS2 nanopores, identifying sequence-specific blockade patterns and distinguishing wild-type from mutant proteins.

bioRxiv · Jul 23, 2025 · PreprintBiophysics