Author

Piotr E. Marszałek

Duke UniversityORCID 0000-0001-7948-8034Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Activity by Year

2025-2025 · peak 1/yr

1 paper

Recent·Most cited

DnaK refolds denatured proteins by actively pulling out their misfolded structural elements

Piotr E. Marszałek

This paper uses AlphaFold3 and molecular dynamics simulations to reveal how DnaK refolds denatured proteins by actively extracting misfolded helices through ATP-driven lid movement.

bioRxiv · Sep 22, 2025 · PreprintBiophysics