LETSmix: a spatially informed and learning-based domain adaptation method for cell-type deconvolution in spatial transcriptomics
Yangen Zhan, Yongbing Zhang, Zheqi Hu, Yifeng Wang, Zirui Zhu, Sijing Du, Xiangming Yan, Xiu Li
LETSmix improves cell-type deconvolution in spatial transcriptomics by integrating spatial context and domain adaptation, achieving better accuracy than existing methods.
Genome Medicine · Feb 28, 2025Peer-reviewedBioinformatics