Lung expression of genes encoding SARS-CoV-2 cell entry molecules and antiviral restriction factors: interindividual differences are associated with age and germline variants
Chiara Elisabetta Cotroneo, Nunzia Mangano, Tommaso Antonio Dragani, Francesca Colombo
The paper identifies eQTLs for APOBEC3D and APOBEC3G in lung tissue, but not for ACE2 or TMPRSS2, suggesting genetic regulation of antiviral genes may influence SARS-CoV-2 infection risk.
European Journal of Human Genetics · Mar 1, 2021Peer-reviewedGenomics