Genetic analyses of the QT interval and its components in over 250K individuals identifies new loci and pathways affecting ventricular depolarization and repolarization
William John Young, Najim Lahrouchi, Aaron J. Isaacs…·Antônio Luiz Pinho Ribeiro
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Oulu University HospitalORCID 0000-0001-8800-963XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
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William John Young, Najim Lahrouchi, Aaron J. Isaacs…·Antônio Luiz Pinho Ribeiro
Rebecca N. Mitchell, Foram N. Ashar, Marjo‐Riitta Järvelin…·Dan E. Arking
The paper examines how sex and underlying disease influence the genetic link between prolonged QT interval and sudden cardiac death risk using logistic regression and Mendelian randomization.
Foram N. Ashar, Rebecca N. Mitchell, Christine M. Albert…·Nona Sotoodehnia
This study evaluates the genetic architecture of sudden cardiac arrest through GWAS and Mendelian randomization, finding genetic correlations with CAD, height, BMI, and electrical instability traits.