DNA spontaneously wrapping around a histone core prefers negative supercoiling: A Brownian dynamics study
Chunhong Long, Hongqiong Liang, Biao Wan
This paper uses a Brownian dynamics model to show that negative supercoiled DNA preferentially wraps around histone cores, influencing nucleosome formation and chromatin dynamics.
PLoS Computational Biology · Jan 28, 2025Peer-reviewedBiophysics