Opioid withdrawal produces sex-specific effects on fentanyl-vs.-food choice and mesolimbic transcription
E. Andrew Townsend, R. Kijoon Kim, Hannah L. Robinson, Samuel A. Marsh, Matthew L. Banks, Peter J. Hamilton
This study shows that opioid withdrawal leads to sex-specific changes in fentanyl choice and mesolimbic gene expression in rats, with males showing increased fentanyl preference and females showing transcriptional hyperfunction.
Biological Psychiatry Global Open Science · May 6, 2021Peer-reviewedNeuroscience