Visualization and Modeling of Inhibition of IL-1β and TNFα mRNA Transcription at the Single-Cell Level
Daniel Kalb, Huy D. Vo, Samantha Adikari, Elizabeth Hong‐Geller, Brian E. Munsky, James H. Werner
The paper uses single-cell mRNA visualization and mathematical modeling to show how inhibitors block IL-1β and TNF-α expression and reveal their activation pathways.
Scientific Reports · Jul 1, 2021Peer-reviewedSystems Biology