GeneticsFrontiers in GeneticsPeer-reviewed
Including phenotypic causal networks in genome-wide association studies using mixed effects structural equation models
Mehdi M. Momen, Ahmad Ayatollahi Mehrgardi, Mahmoud Amiri Roudbar…·Daniel Gianola B
The paper applies structural equation models to GWAS in chickens to decompose SNP effects into direct, indirect, and total effects, showing greater insight into causal relationships than traditional multi-trait methods.