Heritable single-cell gene expression states shape functional variability in innate immune responses
Juan Alfonso Redondo, Nguyen Truong Co, Nissrin Alachkar, Josephine C. Moran, Apurv Srivastav, Marek Kochańczyk, Mark R. Muldoon, Ian S. Roberts, Agata Krawczyk-Balska, Abhyudai Singh, Pawel Paszek
The paper identifies heritable single-cell gene expression states in macrophages and shows how they influence immune response variability and infection outcomes.
bioRxiv · Jun 19, 2026 · PreprintImmunology