Systems BiologyRoyal Society Open SciencePeer-reviewed
Inferring transcriptional bursting kinetics from single-cell snapshot data using a generalized telegraph model
Songhao Luo, Zhenquan Zhang, Zihao Wang…·Jiajun Zhang
This paper introduces a generalized telegraph model and Bayesian inference method to infer transcriptional burst kinetics from single-cell data, showing improved accuracy over classical models.