Kinetic modelling of β-cell metabolism reveals control points in the insulin-regulating pyruvate cycling pathways
Rahul Rahul, Adam R. Stinchcombe, Jamie W. Joseph, Brian Ingalls
This study develops a kinetic model of β-cell metabolism to identify key regulatory points in pyruvate cycling pathways involved in insulin secretion and NADPH production.
IET Systems Biology · Nov 8, 2023Peer-reviewedSystems Biology