Author

Dachang Dang

Northwestern Polytechnical UniversityORCID 0000-0002-0184-6265Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:graph neural network· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Ran DuaniD· 2 shared Shao-Wu ZhangiD· 2 shared Kangning DongiD· 1 shared Shao‐Wu ZhangiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 5 mutual co-author links

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2 shared papersBioinformatics

Ran DuanORCID

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2 papers

Recent·Most cited

BioinformaticsNucleic Acids ResearchPeer-reviewedDec 27, 2024

Uncovering topologically associating domains from three-dimensional genome maps with TADGATE

Dachang Dang, Shao-Wu Zhang, Kangning Dong, Ran Duan

TADGATE identifies TADs from sparse Hi-C maps, enhances their structure, and reveals functional elements and cell-type-specific regulatory mechanisms.

7 citations

humanHi-C

BioinformaticsGenome ResearchPeer-reviewedMar 1, 2023

Defining the separation landscape of topological domains for decoding consensus domain organization of 3D genome

Dachang Dang, Shao‐Wu Zhang, Ran Duan, Shihua Zhang

The paper defines a TAD separation landscape to address inconsistencies in TAD identification across methods and identifies Consensus Topological Associating Domains.

12 citations

Hi-Cstatistical model