Liver microbiome composition associates with histological severity and PNPLA3 genotype in metabolic dysfunction-associated steatotic liver disease
María Florencia Mascardi, R. Taussig, Ivan Privitera Signoretta, Bárbara Suarez, Sebastián Marciano, Paola Cecilia Casciato, Adrián Narvaez, Leila Haddad, Adrian Carlos Gadano, Alberto Penas Steinhardt, Juan P. Bustamante, Julieta Trinks
This study examines the hepatic microbiome in MASLD, finding associations between microbial composition, histological severity, and PNPLA3 genotype, with implications for genomic instability and disease progression.
bioRxiv · Jul 1, 2026 · PreprintMolecular Biology