Structure-derived synthetic sequences guide a protein language model toward metalloproteins
Giulia Peteani, Gianmattia Sgueglia, Thomas Lemmin, Marco Chino
The paper fine-tunes a protein language model using synthetic metalloprotein sequences to improve recovery of metal-binding motifs and identifies novel metal-binding sites.
bioRxiv · May 5, 2026 · PreprintBioinformatics