Author

Polina Polunina

University of FreiburgORCID 0000-0002-0507-4602Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Approach:deep learning· 1 Organism:human· 1 Research Focus:imputation· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

Alan F. RubiniD· 2 shared Wolfgang MaieriD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersBioinformatics

Alan F. RubinORCID

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2 papers

Recent·Most cited

Tree-aware conditional language modeling recovers mutational patterns of viral evolution

Polina Polunina, Wolfgang Maier, Alan F. Rubin

The paper introduces evoPLM-Tree, a tree-aware language model that predicts viral mutations by incorporating phylogenetic context, showing it captures mutational patterns and functional constraints in SARS-CoV-2 spike protein evolution.

bioRxiv · Aug 26, 2026 · PreprintBioinformatics

VEFill: a model for accurate and generalizable deep mutational scanning score imputation across protein domains

Polina Polunina, Wolfgang Maier, Alan F. Rubin

VEFill is a gradient boosting model that imputes missing DMS scores across protein domains, achieving strong predictive performance and generalization to new proteins.

Molecular Systems Biology · Mar 20, 2026Peer-reviewedBioinformatics