MicrobiologyPLoS PathogensPeer-reviewed
Large-scale phenotyping and comparative genomics reveal genetic features of Listeria persistence in epithelial cells
Aurélie Lotoux, Matthieu Bertrand, Pierre-Emmanuel Douarre…·Eliane Milohanic
This study identifies folate biosynthesis as critical for Listeria monocytogenes persistence in epithelial cells by regulating ActA levels and activity, revealing a metabolic pathway that enables vacuolar dormancy.