How thermostable direct haemolysin (TDH) diverges from TDH-related haemolysin (TRH)? Reassessing haemolysins in Vibrio parahaemolyticus through functional and structural representation learning
Zhuosheng Liu, Zhou Yi, Chengchu Liu, C. Titus Brown, Luxin Wang
This study compares TDH and TRH in Vibrio parahaemolyticus using sequence, structure, and function analysis to show their conserved core function with divergent evolutionary paths driven by accumulated mutations.
bioRxiv · Sep 3, 2026 · PreprintMicrobiology