Cell-Type Specific Single-Cell Signatures Reveal Nephrotoxic Drug Effects
Aditi Kuchi, Jose Miguel Acitores Cortina, Hongyu Liu, Yasaman Fatapour, Jacob S. Berkowitz, Nicholas P. Tatonetti
The paper identifies cell-type specific single-cell signatures that reveal nephrotoxic drug effects and improves prediction of drug-induced kidney injury compared to bulk RNA sequencing.
bioRxiv · Jun 17, 2025 · PreprintBioinformatics