Synergistic induction of a lethal Autosis-to-Apoptosis switch by phytocannabinoids and β-Caryophyllene in Triple-Negative Breast Cancer Cells
Carla Hamann, Olivia Jansen, Kateline Jullien, Liza Lhonneux, Allison Ledoux, Michel Frédérich, Erik Maquoi
This study identifies synergistic interactions between phytocannabinoids and β-caryophyllene in TNBC cells, revealing a two-stage death programme involving autosis followed by apoptosis.
bioRxiv · Apr 7, 2026 · PreprintPharmacology & Toxicology