Molecular BiologyNucleic Acid TherapeuticsPeer-reviewed
Transcriptome-Wide Off-Target Effects of Steric-Blocking Oligonucleotides
Erle M. Holgersen, Shreshth Gandhi, Yongchao Zhou…·Amit G. Deshwar
This study evaluates off-target effects of steric-blocking oligonucleotides using RNA-seq and finds that in silico methods have limited utility for predicting these effects.
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