Simulated complexes formed from a set of postsynaptic proteins suggest a localised effect of a hypomorphic Shank mutation
Marcell Miski, Áron Weber, Krisztina Fekete-Molnár, Bence Márk Keömley-Horváth, Attila Csikász‐Nagy, Zoltán Gáspári
The paper models the effects of a hypomorphic Shank mutation on protein complex formation in postsynaptic densities, showing that mutation impacts depend on protein availability and cell type.
BMC Neuroscience · Jul 6, 2024Peer-reviewedSystems Biology