Author

A. Dean Befus

University of AlbertaORCID 0000-0002-1611-2897Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Research Focus:protein folding & dynamics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Joy Ramielle L. SantosiD· 2 shared Marcelo Marcet-PalaciosiD· 2 shared Eun Bin MooniD· 1 shared Maya MacIsaac· 1 shared Weijie SuniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersGenomics

Joy Ramielle L. SantosORCID

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2 papers

Recent·Most cited

MaaD-TAD: an all-atom model of the duplicated PRAMEF/HNRNPCL chromatin domain built from sequence homology

Joy Ramielle L. Santos, Maya MacIsaac, Eun Bin Moon, A. Dean Befus, Marcelo Marcet-Palacios

The paper introduces MaaD-TAD, an all-atom model of a duplicated chromatin domain, using sequence homology and cohesin placement to reconstruct DNA structure where Hi-C data are missing.

bioRxiv · Nov 9, 2026 · PreprintGenomics

SEQSIM - A novel bioinformatics tool for comparisons of upstream gene regions - a case study of calcium binding protein spermatid associated 1 (CABS1)

Joy Ramielle L. Santos, Weijie Sun, A. Dean Befus, Marcelo Marcet‐Palacios

SEQSIM is a bioinformatics tool for comparing upstream gene regions, demonstrating its ability to identify regulatory clusters and motifs in the human genome through a case study of CABS1.

bioRxiv · May 3, 2024 · PreprintBioinformatics