Author

Leona Sharma

University College LondonORCID 0000-0002-1644-586XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

David CurtisiD· 1 shared Kaushiki Bakaya· 1 shared Sreejan Bandyopadhyay· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperGenetics

David CurtisORCID

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1 paper

Recent·Most cited

Weighted burden analysis of exome-sequenced late onset Alzheimer’s cases and controls provides further evidence for a role for PSEN1 and suggests involvement of the PI3K/Akt/GSK-3β and WNT signalling pathways

David Curtis, Kaushiki Bakaya, Leona Sharma, Sreejan Bandyopadhyay

The paper uses weighted burden analysis on exome data from over 10,000 Alzheimer's cases and controls to find PSEN1 as a risk factor and suggest roles for PI3K/Akt/GSK-3β and WNT pathways.

Annals of Human Genetics · Feb 5, 2020Peer-reviewedGenetics