Author

Martin Schüle

Johannes Gutenberg University MainzORCID 0000-0002-1677-0232Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Jennifer WinteriD· 1 shared Kristina EndresiD· 1 shared Laura Schlichtholz· 1 shared Sri Dewi· 1 shared Susann SchweigeriD· 1 shared Susanne GerberiD· 1 shared Susanne Strand· 1 shared Tamer ButtoiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperNeuroscience

Jennifer WinterORCID

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1 paper

Recent·Most cited

mTOR driven gene transcription is required for cholesterol production in neurons of the developing cerebral cortex

Martin Schüle, Tamer Butto, Sri Dewi, Laura Schlichtholz, Susanne Strand, Susanne Gerber, Kristina Endres, Susann Schweiger, Jennifer Winter

This study identifies mTORC1 as a transcriptional regulator of cholesterol biosynthesis genes in developing neurons, linking mTOR activity to cholesterol production and neurodevelopmental disorders.

bioRxiv · Sep 4, 2020 · PreprintNeuroscience