Author

Stefan W. Toennes

Goethe University FrankfurtORCID 0000-0002-1774-3201Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:statistical model· 5 Assay:imaging· 4 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Johannes Gerardus RamaekersiD· 6 shared Natasha Leigh MasoniD· 6 shared Pablo MallaroniiD· 4 shared Eef Lien TheunisseniD· 3 shared Enrico AmicoiD· 3 shared Johannes T. ReckwegiD· 2 shared Kim P. C. KuypersiD· 2 shared Aline Frick· 1 shared

Activity by Year

2019-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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6 shared papersNeuroscience

Johannes Gerardus RamaekersORCID

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6 papers

Recent·Most cited

Tuning in together: LSD enhances inter-brain synchrony and felt connectedness in romantic couples

Natasha Leigh Mason, Artur Czeszumski, Iva Totomanova, Filip Trbusek, Mauro Cavarra, Stephanie M. Ashton, Stefan W. Toennes, Eef Lien Theunissen, Johannes T. Reckweg, Patricia L. Lockwood, Marieke D. Dewitte, Katrin H. Preller, Kim P. C. Kuypers, Guillaume Dumas, Pablo Mallaroni, Johannes Gerardus Ramaekers

This study shows that LSD increases inter-brain synchrony and felt connectedness in romantic couples during rest and interaction, independent of drug concentration.

bioRxiv · Aug 21, 2026 · PreprintNeuroscience

Sex Differences in Acute Responses to Psychedelics: Evidence for Greater Subjective Intensity and Impairment in Female Participants

Natasha Leigh Mason, Eline C. H. M. Haijen, Kim P. C. Kuypers, Aline Frick, Stefan W. Toennes, Pablo Mallaroni, Johannes Gerardus Ramaekers

This study finds that female participants report greater subjective intensity and impairment during acute psychedelic experiences compared to males, independent of drug exposure and age.

bioRxiv · Aug 19, 2026 · PreprintNeuroscience

Unmixing the Psychedelic Connectome: Brain Network Traits of Psilocybin

Krishna Prasad Bhavaraju, Natasha Leigh Mason, Pablo Mallaroni, Dietmar G. Heinke, Stefan W. Toennes, Johannes Gerardus Ramaekers, Enrico Amico

This study uses connICA to analyze resting-state fMRI data and identifies distinct functional connectivity traits associated with psilocybin's effects on brain networks and cognitive performance.

Network Neuroscience · Jan 1, 2026Peer-reviewedNeuroscience

Ritualistic use of ayahuasca enhances a shared functional connectome identity with others.

Pablo Mallaroni, Natasha Leigh Mason, Lilian Kloft, Johannes T. Reckweg, Kim I. M. van Oorsouw, Stefan W. Toennes, Hanna M. Tolle, Enrico Amico, Johannes Gerardus Ramaekers

This study examines how ayahuasca use affects functional connectomes, finding shared functional spaces and predictive relationships between connectivity patterns and drug experiences.

bioRxiv · Oct 7, 2022 · PreprintNeuroscience

Spatial patterns in functional brain connectomes reflect acute and chronic cannabis use.

Johannes Gerardus Ramaekers, Natasha Leigh Mason, Stefan W. Toennes, Eef Lien Theunissen, Enrico Amico

The paper identifies spatial patterns in functional brain connectomes that distinguish acute from chronic cannabis use using whole-brain network analysis.

bioRxiv · Mar 8, 2021 · PreprintNeuroscience

Reduced responsiveness of the reward system underlies tolerance to cannabis impairment in chronic users

Natasha Leigh Mason, Eef Lien Theunissen, Nadia R. P. W. Hutten, Desmond H. Y. Tse, Stefan W. Toennes, Jacobus F.A. Jansen, Peter L. J. Stiers, Johannes Gerardus Ramaekers

This study shows chronic cannabis users show reduced reward system responsiveness to cannabis, leading to tolerance to its impairing effects.

Addiction Biology · Dec 22, 2019Peer-reviewedNeuroscience