BiophysicsbioRxivPreprint
Pentose Sugars Encode Sequence-Dependent DNA-RNA Segregation for Programmable Engineering of Multiphase Condensates
Wei Peng Guo, Feipeng Chen, Andrew B. Kinghorn…·Ho Cheung Shum
The paper shows that a single sugar difference between DNA and RNA drives phase segregation with cationic peptides, enabling programmable synthetic condensates that mimic nuclear compartments.
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