Author

Wei Peng Guo

Shenzhen UniversityORCID 0000-0003-3634-0077Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Andrew B. KinghorniD· 1 shared Chunmu Yin· 1 shared Dawei Meng· 1 shared Dongsheng FaniD· 1 shared Feipeng CheniD· 1 shared Haipeng GongiD· 1 shared Haohui Ou· 1 shared Ho Cheung ShumiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Andrew B. KinghornORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJun 23, 2025

Pentose Sugars Encode Sequence-Dependent DNA-RNA Segregation for Programmable Engineering of Multiphase Condensates

Wei Peng Guo, Feipeng Chen, Andrew B. Kinghorn…·Ho Cheung Shum

The paper shows that a single sugar difference between DNA and RNA drives phase segregation with cationic peptides, enabling programmable synthetic condensates that mimic nuclear compartments.

2 citations

DNA methylationChIP-seq

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NeurosciencebioRxivPreprintJan 9, 2025

Title: Cell-autonomous and non-cell-autonomous effects of TRIM72 on ALS disease progression

Xue Zhang, Ji He, Ning Song…·Yichang Jia

This study identifies TRIM72's protective role in ALS through both cell-autonomous and non-cell-autonomous mechanisms, showing its therapeutic potential in animal models and human patients.

3 citations

humanproteomics

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