Author

Michelle M. Chang

ORCID 0000-0002-1998-6047Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alec A. K. NielseniD· 1 shared Dinghai ZhengiD· 1 shared Jennitte L. StevensiD· 1 shared Jeremy J GamiD· 1 shared Kevin D. Smith· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperBioengineering

Alec A. K. NielsenORCID

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1 paper

Recent·Most cited

Optimizing Bispecific Antibody Expression via Multi-Omics Analysis and Vector Redesign

Jeremy J Gam, Michelle M. Chang, Dinghai Zheng, Jennitte L. Stevens, Alec A. K. Nielsen, Kevin D. Smith

This study improves bispecific antibody expression by analyzing multi-omics data and redesigning vectors, resulting in an 11-fold increase in stable titers.

Biotechnology and Bioengineering · May 6, 2026Peer-reviewedBioengineering