Predicting cell fate commitment of embryonic differentiation by single-cell graph entropy
Jiayuan Zhong, Chongyin Han, Xuhang Zhang, Pei Chen, Rui Liu
This study introduces single-cell graph entropy (SGE) to predict cell fate commitment in embryonic differentiation using scRNA-seq data, identifying critical transitions not detectable by gene expression alone.
bioRxiv · Apr 22, 2020 · PreprintBioinformatics