Author

Hélène Leclerc

AgroParisTechORCID 0000-0002-2103-2234Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Anne BarbatiD· 2 shared Arnaud BoullingiD· 2 shared Aurélien CapitaniD· 2 shared Cécile GrohsiD· 2 shared Didier BoichardiD· 2 shared Mekki BoussahaiD· 2 shared Raphaël R. GuatteoiD· 2 shared Sébastien FritziD· 2 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Anne BarbatORCID

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2 papers

Recent·Most cited

A bovine model of rhizomelic chondrodysplasia punctata caused by a deep intronic splicing mutation in the GNPAT gene

Arnaud Boulling, Julien Corbeau, Cécile Grohs, Anne Barbat, Jeremy Raphael Mortier, Sébastien Taussat, Vincent Plassard, Hélène Leclerc, Sébastien Fritz, Cyril Leymarie, Lorraine Bourgeois‐Brunel, Alain Ducos A, Raphaël R. Guatteo, Didier Boichard, Mekki Boussaha, Aurélien Capitan

The paper identifies a deep intronic splicing mutation in the GNPAT gene in cattle causing rhizomelic chondrodysplasia punctata, and demonstrates its phenotypic effects through genetic and functional analyses.

bioRxiv · Jun 13, 2024 · PreprintGenetics

Massive detection of cryptic recessive genetic defects in cattle mining millions of life histories

F. Besnard, Ana Guintard, Cécile Grohs, Laurence Guzylack‐Piriou, Margarita Cano, Clémentine Escouflaire, Chris Hozé, Hélène Leclerc, Thierry Buronfosse, Lucie Dutheil, Jeanlin Jourdain, Anne Barbat, Sébastien Fritz, Marie-Christine Deloche, Aude Rémot, , Aurélien Capitan

The paper detects recessive genetic defects in cattle using genomic data and life history analysis, identifying 33 new loci linked to juvenile mortality.

bioRxiv · Sep 22, 2023 · PreprintGenetics