Author

Karin Ekstrom Ekstroem Smedby

Karolinska University HospitalORCID 0000-0002-2104-3320Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alyssa C. BouskaiD· 1 shared Andreas RosenwaldiD· 1 shared Andrew J. GentlesiD· 1 shared Ash A. AlizadehiD· 1 shared Chih Long LiuiD· 1 shared Christine J. Pak· 1 shared Dalia Y. MooreiD· 1 shared Dhiraj KumariD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Alyssa C. BouskaORCID

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1 paper

Recent·Most cited

Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in the activated B-cell subtype of diffuse large B-cell lymphoma

Neeraj Kumar Jain, Keenan T. Hartert, Saber Tadros, Warren C. Fiskus, Ondřej Havránek, Man Chun John Ma, Alyssa C. Bouska, Tayla B. Heavican, Dhiraj Kumar, Qing Deng, Dalia Y. Moore, Christine J. Pak, Chih Long Liu, Andrew J. Gentles, Elena Hartmann, , Michael R. Green

The paper identifies TCF4 overexpression driven by 18q21.2 gains as a mechanism promoting IgM expression in ABC-like DLBCL and shows BET inhibitors can suppress it.

Science Translational Medicine · Jun 19, 2019Peer-reviewedGenomics