STIM1 transmembrane helix dimerization captured by AI-guided transition path sampling
Ferdinand Horvath, Hendrik Jung, Herwig Grabmayr, Marc Fahrner, Christoph Romanin, Gerhard Hummer
This paper uses AI-guided simulations to study STIM1 TM-helix dimerization, revealing three coexisting configurations and reconciling conflicting experimental results.
Proceedings of the National Academy of Sciences · Aug 26, 2025Peer-reviewedBiophysics