Author

Charles N. Agoti

Kenya Medical Research InstituteORCID 0000-0002-2160-567XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:variant calling· 1 Organism:virus· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Arnold W. LambisiaiD· 2 shared A. KonéiD· 1 shared Abdel‐Rahman N. ZekriiD· 1 shared Abdoul Karim SangaréiD· 1 shared Abdoul–Salam OuédraogoiD· 1 shared Abdul Karim SesayiD· 1 shared Adedotun-Sulaiman Kemi· 1 shared Adewunmi M. Olubusuyi· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Arnold W. LambisiaORCID

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2 papers

Recent·Most cited

Viral Diversity Influences T Cell Responses to Enteric Human Adenoviruses F40 and F41

Holly M. Craven, Jennifer P. Hoang, Rookmini Mukhopadhyay, Arnold W. Lambisia, Benjamin A. Krishna, Benjamin J. Ravenhill, Charles N. Agoti, Charlotte J. Houldcroft

The paper identifies CD8+ T cell epitopes in HAdV-F40 and F41 hexon and penton proteins, showing they elicit IFNγ responses in healthy donors and could inform vaccine design.

Virus Evolution · Dec 12, 2025Peer-reviewedMicrobiology

A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa

Eduan Wilkinson, Marta Giovanetti, Houriiyah Tegally, James Emmanuel San, Richard J. Lessells, Diego F. Cuadros, Darren Patrick Martin, David A. Rasmussen, Abdel‐Rahman N. Zekri, Abdoul Karim Sangaré, Abdoul–Salam Ouédraogo, Abdul Karim Sesay, Priscilla Abechi, Adedotun-Sulaiman Kemi, Adewunmi M. Olubusuyi, , Gabriel K. Mbunsu

This study uses genomic data from 8746 SARS-CoV-2 genomes across 33 African countries to show that most epidemics were initiated by European importations and later driven by local transmission and mobility, leading to the spread of variants of concern.

Science · Oct 9, 2021Peer-reviewedGenetic & Genomic Medicine