Analysis of Alzheimer's disease Polygenic Risk Scores using RNA-sequencing provides further novel biological pathways
Karen L. Crawford, Ganna Leonenko, Emily Ann Baker, Detelina Grozeva, Benoît Lan-Leung, Peter Holmans, Julie H. Williams, Michael C. O’Donovan, Valentina Escott‐Price, Dobril K. Ivanov
The paper analyzes Alzheimer's disease polygenic risk scores using RNA-sequencing to identify novel biological pathways and common mechanisms between case/control classification and PRS associations.
medRxiv · Jun 29, 2022 · PreprintGenetic & Genomic Medicine