Author

Roland Wittler

Bielefeld UniversityORCID 0000-0002-2249-9880Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 6

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Assay:whole-genome sequencing· 3 Research Focus:benchmarking· 2 Research Focus:phylogenetics / evolution· 2 Research Focus:clustering· 1 Research Focus:database / resource· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Jens StoyeiD· 3 shared Andreas RempeliD· 2 shared Daria FrolovaiD· 1 shared Fabian Kolesch· 1 shared Faraz HachiD· 1 shared Leah Wendy RobertsiD· 1 shared Leandro LimaiD· 1 shared Leonard BohnenkämperiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersBioinformatics

Jens StoyeORCID

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6 papers

Recent·Most cited

SANS ambages: phylogenomics with abundance-filter, multi-threading, and bootstrapping on amino-acid or genomic sequences

Fabian Kolesch, Marco Sohn, Andreas Rempel, P Von Hippel, Roland Wittler

SANS ambages improves phylogeny estimation by adding amino-acid support, parallel processing, and bootstrapping for genomic and sequencing data.

BMC Bioinformatics · Sep 2, 2025Peer-reviewedBioinformatics

Applying rearrangement distances to enable plasmid epidemiology with pling

Daria Frolova, Leandro Lima, Leah Wendy Roberts, Leonard Bohnenkämper, Roland Wittler, Jens Stoye, Zamin Iqbal

This paper introduces pling, a tool that uses rearrangement distances to cluster plasmids more accurately by accounting for structural changes and avoiding over-clustering caused by transposable elements.

Microbial Genomics · Oct 14, 2024Peer-reviewedBioinformatics

Revisiting pangenome openness with k-mers

Luca Parmigiani, Roland Wittler, Jens Stoye

The paper estimates pangenome openness using k-mers instead of genes and compares the results, providing an efficient implementation.

Peer Community Journal · Apr 23, 2024Peer-reviewedBioinformatics

General encoding of canonical k-mers

The paper introduces a minimal encoding for canonical k-mers that evenly distributes them in a reduced interval, improving efficiency for sequence indexing and comparison.

Peer Community Journal · Sep 20, 2023Peer-reviewedBioinformatics

SANS serif: alignment-free, whole-genome based phylogenetic reconstruction

Andreas Rempel, Roland Wittler

SANS serif estimates phylogenies using alignment-free whole-genome data through a pangenomic approach.

Bioinformatics · Jun 15, 2021Peer-reviewedBioinformatics

Detecting High Scoring Local Alignments in Pangenome Graphs

Tizian Schulz, Roland Wittler, Sven Rahmann, Faraz Hach, Jens Stoye

The paper introduces a heuristic method for finding high-scoring local alignments of DNA queries to pangenome graphs and demonstrates its scalability and effectiveness.

Bioinformatics · Jan 28, 2021Peer-reviewedBioinformatics