A supervised learning framework for chromatin loop detection in genome-wide contact maps
Tarik J. Salameh, Xiaotao Wang, Fan Song, Bo Zhang, Sage M. Wright, Chachrit Khunsriraksakul, Yijun Ruan, Feng Yue
This paper introduces Peakachu, a Random Forest framework for chromatin loop detection in Hi-C data, showing improved identification of short-range interactions across multiple platforms and species.
Nature Communications · Jul 9, 2020Peer-reviewedBioinformatics