Modeling of the Network Mediated by IL-36 Involved inPsoriasis
Sneha Pandey, Syona Tiwari, Sulagna Basu, Rajiv Kumar Mishra, R. Pandey
The paper constructs a network and mathematical model of IL-36-mediated cell interactions to show that increased IL-36 leads to keratinocyte hyper-proliferation and Psoriasis, with potential for switch-like behavior and treatment strategies.
bioRxiv · Jul 3, 2023 · PreprintSystems Biology