John E. Straub

Accurate determination of the preferred aggregation number of a micelle-encapsulated membrane protein dimer

The paper determines the preferred aggregation number of DPC micelles encapsulating a membrane protein dimer using molecular dynamics simulations and finds it differs from the pure micelle value.

Exploring the kinetics and mechanism of phase separation in ternary lipid mixtures containing APP C99 using atomistic vs coarse-grained MD simulations

This study uses atomistic and coarse-grained MD simulations to investigate the kinetics and mechanism of phase separation in ternary lipid mixtures containing APP C99, identifying three distinct time regimes.

Molecular basis for a novel systemic form of human hereditary apoA-I amyloidosis with vision loss

The paper identifies a novel form of hereditary apoA-I amyloidosis caused by Glu34Lys mutation, revealing structural changes that lead to amyloid formation and vision loss.