Whole-genome sequencing in mitral valve prolapse: an exploratory study on genes associated with mitral valve prolapse and cardiac arrhythmias
Nikhil Arora, Julie Van Den Bergh, Christine Rootwelt‐Norberg, Christian K Five, Bjørn Olav Åsvold, Brooke N. Wolford, Cecilie Bugge, Anna Isotta Castrini, Nina E. Hasselberg, John‐Peder Escobar Kvitting, Eivind Coward, Kristian Hveem, Kristina Hermann Haugaa
This study uses whole-genome sequencing to identify genetic variants associated with mitral valve prolapse and arrhythmias in a Norwegian cohort, finding enriched variants in genes related to extracellular matrix and electrophysiological pathways.
medRxiv · Sep 7, 2026 · PreprintGenetic & Genomic Medicine